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#mounjaro

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New Review and Meta-Analysis confirms weight gain with discontinuance of #Semaglutide and #Tirzepatide

Discontinuing GLP1 medications led to a pooled overall mean weight regain of 9.69 kg (or about 22 lbs in patients prescribed semaglutide/tirzepatide. The proportion of weight regained was proportional to the amount originally lost.

Discontinuation of GLP-1RA treatment leads to weight regain, regardless of lifestyle interventions, and should therefore be considered a chronic therapy to prevent weight regain and associated undesirable outcomes related to #Obesity.

#wegovy #ozempic #mounjaro #zepbound
onlinelibrary.wiley.com/doi/10

GLP-1s Are Crazy Effective — Just Not Cost-Effective

I’ll make the argument that the most effective drugs in the past decade are the GLP-1 receptor agonists, drugs like semaglutide and tirzepatide. At least in terms of weight loss, they are truly unparalleled. They are clearly effective. But are they worth it? Are they cost-effective? That is a much harder question, and, as you’ll see in a minute, despite their amazing effects, the answer — for now, at least — is no.

#mounjaro #ozempic #zepbound #wegovy #glp1
medscape.com/viewarticle/glp-1

Medscape · GLP-1s Are Crazy Effective — Just Not Cost-EffectiveBy F. Perry Wilson, MD, MSCE

Auwei da kann einem ja Angst und Bange werden.
Da muss ich sofort Dokta Guugel befragen und medizinalheilkräftige Webseiten studieren 🔍 👀

Zitat:
#Semaglutid und #Tirzepatid ( #Wegovy #Ozempic #mounjaro ) werden seit langem als Durchbruch im Kampf gegen #Fettleibigkeit und #Typ2Diabetes gepriesen.
- angeblich auch schwere psychische Probleme auslösen
-mehr als 2000 Nutzer der Injektionen - Hilfe wegen #Panikattacken und schwerer #Angstzustände gesucht haben

bz-berlin.de/ratgeber/abnehmsp

B.Z. – Die Stimme Berlins · Löst Abnehmspritze Angstattacken aus? Tausende BetroffeneDickes Geschäft mit Abnehmspritzen! Doch neben den positiven Eigenschaften gibt es immer wieder Berichte über gefährliche Nebenwirkungen.

Forget Psychedelics 😵‍💫

Everyone’s Microdosing Ozempic Now 🤔

“Shamoon has joined the wave of people who are taking limited amounts not of psychedelics — to which the microdosing trend usually applies — but of the diabetes drug #Ozempic (#semaglutide), and other #GLP1 receptor agonists like #Mounjaro

They are doing it not primarily for weight loss — the effect that has made Ozempic a Hollywood staple and a reliable awards-show punchline — but for the surprising and widely touted side benefits, particularly its anti-inflammatory properties”

hollywoodreporter.com/lifestyl

Lilly’s Zepbound Beats Wegovy in First Head-to-Head Study

Eli Lilly’s Zepbound #Obesity drug helped people lose significantly more weight than its main competitor, Novo Nordisk’s Wegovy.

People taking Zepbound lost 20.2% of their body weight on average after 72 weeks of treatment in the Lilly-sponsored study, compared with a 13.7% loss for Wegovy patients, Lilly said Wednesday.

That translated into an average 50-pound loss for people who took Zepbound, while Wegovy users lost 33 pounds.

PS: #Zepbound and #Mounjaro are the same drug with different brand names, as are #Ozempic and #Wegovy.

apple.news/Acy6MzE4uRrORN59ldO

apple.newsEli Lilly’s Zepbound Beats Novo Nordisk’s Wegovy in First Head-to-Head Study — The Wall Street JournalPeople who took Zepbound lost 17 pounds more on average after 72 weeks of treatment than those who were given Novo Nordisk’s drug

Amazing!

GLP-1 medications like #Ozempic and #Mounjaro are reducing ‘all cause’ hospitalizations and bariatric surgery.

Researchers recently found a 132.6% increase in #GLP1 prescriptions and a 25.6% decline in bariatric surgeries between 2022 and 2023. The results add empirical evidence to a trend of declining operations that bariatric surgeons have been noticing for months.

A Novo Nordisk trial also discovered an association between Wegovy prescriptions and fewer hospitalizations for any cause”

#obesity #wegovy #zepbound
beckershospitalreview.com/phar

#Obesity Drug Shows Promise in Easing Knee #Osteoarthritis Pain

As a practicing physician, I've seen up close the remarkable benefits of the #GLP1 class of medications, including #semaglutide (#Ozempic, #Wegovy) and #tirzepatide (#Mounjaro, #Zepbound.)

Reduction in weight (and inflammation) are game changers.

Better control of #Diabetes, reduced #Cardiovascular and #Stroke risk, maybe lower incident of #Dementia, #MultipleSclerosis and other diseases which have an 'inflammatory' component.

All we need now is to lower the cost (about $1,000/month in the US; heard the price is $59 in EU!)

nytimes.com/2024/10/30/health/

Probíral jsem s kámošem ty moje levné náhražky Saxendy, Ozempicu a Mounjara. Poslal jsem mu tu svou "rešerši" a sepsul mě, že jsem neuvedl obyčejné kvasnice. Obyčejné droždí. Málem jsem se pozvracel. 🤮😂
A to prosím neznám osobně druhou osobu, která by droždí jedla, než moje mamka a vždy jsem prchal, abych to neviděl. 😁

Ale je to fakt. Je to extrémně levné. 42g(2g je ten hliníkový obal, bych řekl) balení stojí 5-12 kaček. Je z toho cca 20g čistého betaglukanu, což je skoro ta jedna pomyslná dávka, kterou simulují léky na hubnutí. Takže jedna krychlička denně.

#^https://www.rohlik.cz/1289859-uniferm-drozdi-cerstve
#^https://www.rohlik.cz/1305551-fala-pekarske-drozdi-cerstve

Jako jo, jde to, ale já bych to do sebe nedostal ani párem volů. To raději chroupat půl kila ovsa denně... 🐎

Více viz:
#^https://libera.site/item/a55497fa-97b2-4172-8105-2a7b91c7bd5c

#Betaglukan #Ozempic #Saxenda #Mounjaro #Semaglutide #Liraglutide #Tirzepatide #Kvasnice #Droždí
Rohlik.czUniferm droždí čerstvéČerstvé pekařské droždí neboli kvasnice. PoužitíKvasnice se používají pro pečení chleba a pečiva z kynutého těsta.O výrobciSpolečnost UNIFERM se může

Who needs a #GLP1 when you have this? Move over Ozempic!

"We've developed a molecule that can mimic the body's natural metabolic response to strenuous exercise and fasting.

In practice, the molecule brings the body into a metabolic state corresponding to running 10 kilometers at high speed on an empty stomach," explains Professor Thomas Poulsen from the Department of Chemistry at Aarhus University"

#ozempic #mounjaro #zepbound #wegovy #tirezepatide #semaglutide #obesity #weightloss #longevity
phys.org/news/2024-10-molecule

Phys.org · New molecule can mimic the effects of fasting and exerciseBy Aarhus University
Replied in thread

@3x10to8mps
Sorry for all the trouble you've had 🙁

As I've seen in my practice, most of the side effects can be dealt with dietary changes.

And as usual, in the crazy American #Healthcare system, we have two names for one drug:

#Ozempic (diabetes) and #Wegovy (obesity, with slight difference in dose) = #semaglutide

#Mounjaro (#diabetes) and #Zepbound (#obesity, same exact dose) = #tirezepatide.

I've created this informational instruction page with dietary hints for my patients:

cnmri.com/mounjaro/

Doctors Wish More People Over 65 Took Ozempic

Millions of people are flocking to drugs like #Ozempic and #Wegovy to lose weight and treat health problems. Doctors say one group that could benefit from the drugs is missing out: seniors.

For older people, these medications can help in ways that go beyond losing weight, physicians say. Fewer pounds can lead to more mobility and better balance, allowing older people to become more active. That can boost mood, overall health, and sometimes makes the difference between walking freely or using a wheelchair or cane.

#mounjaro #zepbound #glp1 #obesity
apple.news/Aiz7CIM58Qv-tvbGUuE

apple.newsDoctors Wish More People Over 65 Took Ozempic — The Wall Street JournalInsurance hurdles and worries about muscle loss mean fewer older patients are using weight-loss drugs

Ozempic and cancer: What to know

Labels for #GLP1 medications, like #Ozempic and #Mounjaro, might see more approved uses as researchers study the drugs' effects on #SleepApnea, #Dementia and other health issues. Meanwhile, oncologists are looking at a GLP-1 role in #Cancer care.

Several studies have shown the therapies — currently approved for Type 2 #diabetes and weight loss — can diminish the risk of multiple cancers:

#obesity #glp
beckershospitalreview.com/glp-

Tak jsem si udělal menší rešerši.

Podle #^https://www.sciencealert.com/one-type-of-fiber-could-have-weight-loss-benefits-similar-to-ozempic
by člověk měl do sebe dostat cca 25-30g betaglukanu denně. Ty jsou v kvasnicích, houbách a ovsi.

Extrakt z ovse
#^https://www.pangamin.cz/cardio-well-300g-50g-zdarma_z1540/
40g denně, tedy balení je na cca 10 dnů. Denní dávka stojí cca 40Kč.

Kvasnice
#^https://www.pangamin.cz/pangamin-klasik-sacek_z9/
Cca půlka hmotnosti buňky je betaglukan, takže balení s 90g stačí na cca 2 dny. Denní dávka stojí cca 45Kč.
(hrozně mi to páchne a nedělají to v tobolkách)

Oves
Betaglukanů je v ovsi cca 3-6% hmotnosti. Tzn. 0,5-1kg ovsa denně. 🐎🐴😱

Takže nic moc. Nic koncentrovanějšího jsem zatím nenašel.
Chtělo by to čistý betaglukan. Kdyby někdo měl chuť na startup. To je očividná díra na trhu...


#Betaglukan #Ozempic #Saxenda #Mounjaro #Semaglutide #Liraglutide #Tirzepatide
ScienceAlert · One Type of Fiber Could Have Weight Loss Benefits Similar to OzempicResearch on the gut microbiome has triggered a 'revolution' in nutritional science, and in the last few years, dietary fiber has become the "new protein" – added to foods in abundance to feed our gut and boost our health.