Your govt at work:Paxlovid Medicare with Medigap Insurance: $263. With GoodRX: $1,500. Before the Covid crisis was declared over: Nil. Feels like they'd just assume we die.
Government efficiency, my ass.
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· People with recent COVID-19 at higher risk for other viral and bacterial infections
· A 15-day course of #Paxlovid did not “significantly improve health outcomes in participants with #LongCOVID
· 2. study showed that Paxlovid taken within 5 days of infection with COVID-19 did help with the acute phase of COVID-19 in children
· Rapamycin, a drug used for organ transplants, may help alleviate symptoms of myalgic encephalomyelitis #MECFS
https://thesicktimes.org/2025/04/08/research-updates-april-8/
The Sick Times - Chronicling the Long Covid crisis · Research updates, April 8 - The Sick TimesPeople who recently had COVID-19 are at higher risk for other viral and bacterial infections, according to a paper published in The Lancet Infectious Diseases. The researchers used Veterans Affairs electronic health records from over 800,000 people, and compared infection history between those who had a positive COVID-19 test and those who did not. Those who tested positive had higher rates of bacterial and viral infections, including Epstein-Barr virus and seasonal respiratory viruses, in the year following their COVID-19 diagnosis.
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"Covid Protocol" goes like this:
Sick person isolated in room, block door with towel, only come through rest of house with #N95 briefly. Tray table outside door for food drop off. Disinfect everything.
#paxlovid ASAP for sick, lower #covid damage.
Heater off, open windows, box fans in windows to make positive pressure in main house, negative pressure in sick room, dumping sick air out bedroom window.
Constant air flow.
Yes, we fucking freeze.
All-clear when RAT clear, and nobody sick.
"There are over 200 different symptoms that can appear in any different combination. And then the other piece about it is there are about six different mechanisms of what can be causing long COVID. So everyone has in common COVID as the thing that started their long COVID.
However, there are so many different physiological things going wrong in different people with long COVID, they might require different treatments."
"There are actually a lot of great trials going on [...] one looking at mitochondrial dysfunction is Rapamycin, which David Petrino’s group is running."
"There’s a few looking at immunomodulation with JAK inhibitors, both the Baricitinib trial by Wes Eli’s group and another JAK inhibitor trial that’s starting at Harvard. Another immunomodulation option is IVIG, which is being run by the NIH RECOVER consortium. This one’s tricky because it’s not super scalable. You have to get the antibodies from people and then infuse them into other people"
"And then the other mechanism that’s being looked at a lot now is viral persistence, both through a few different monoclonal antibodies trials– Michael Peluso’s, funded by the Patient Led Research Collaborative. Nancy Klimas is just starting one funded by the Schmidt Initiative for Long COVID and the state of California. And then there’s another one in Italy that’s funded by industry, all looking at monoclonal antibodies. And then the last viral persistence one is also being run by the Petrino group on Truvada, which is an HIV antiviral."
Science Friday · Can Paxlovid Relieve Long COVID Symptoms? For Some, Yes
Replied in thread
@MaksiSanctum thank you for this information, last year I asked my doctor if I should take this or #Paxlovid if I tested positive and he said paxlovid, but the box I have expired in the spring of 2023 I think, and now insurance doesn’t cover it so I’m not sure if I could get a fresh one. I’m going to drop this link in the portal for him.
After 5 years of fighting to not get #COVID, wearing masks, not eating indoors, etc. I finally tested positive after my dad’s funeral.
I’ve had every vaccine and booster and so far the symptoms are very mild. 72 hours after exposure:
- Chills; but no fever.
- Body aches
- Slight soar throat
- Little appetite
Not a candidate for #Paxlovid even with #UC since I’m not on an immunotherapy.
I’m hoping it passes quickly.
Jut, jut... Rebound-Effekt nach #Paxlovid.*
Was wissen wir darüber? 
(Mein Stand bisher: Es soll mild(er) sein. Symptome bekämpfen, nicht erneut Paxlovid. Richtig? Falsch? Bitte Quellen.)
*War klar, dass ich das auch wieder abgreife, wa?
Paxlovid hilft einigen Patienten mit LongCovid. Macht Sinn, denn wir wissen, dass das Virus bei viel mehr Menschen im Körper bleibt, als wir dachten.
Die Packung kostet in der Schweiz etwa 1000 Franken. Wird meist nicht durch die Versicherung übernommen. Die Ärzte verschreiben es aber auf Wunsch wenn man einen positiven Schnelltest und LongCovid als Vorerkrankung angibt. (Nen bissle telefonieren, vielleicht verschreibt es erst der Dritte)
NatureImpact of extended-course oral nirmatrelvir/ritonavir in established Long COVID: a case series - Communications MedicineCohen et al. report a patient-led case series of 13 individuals with Long COVID who initiated extended courses of Paxlovid outside of, or within the context of, an acute SARS-CoV-2 infection. Long courses of nirmatrelvir/ritonavir have meaningful benefits for some people with Long COVID but not all.
Omg.
An elderly family member is in the ER for a fall. This person is 83, has Parkinson's Disease, and is a lifelong smoker. While in the ER, they tested positive for covid.
Their caregiver requested #Paxlovid and reports, "The doctor that was here was like we don't prescribe that and it doesn't work. That is exactly what she said."
?!?!
1/2
Final (hopefully!) #covid update.
I have a lingering cough and stuffy nose to remind me of my recent – and only 2nd – bout of Covid. My first 2 1/2 days of fever were pretty bad. I didn’t get Paxlovid because of knowing of several people who took it and then relapsed. Just my own personal decision and experience. Fortunately, it never went into my lungs; if it had, I definitely would have gone the #paxlovid route.
I’m so glad I got my booster shot in November! Could’ve been much worse…
Effect of #paxlovid on adverse outcomes from #COVID19 in kidney disease. Acknowledging the limitations of a propensity-score matched study, use was associated with 
hospitalizations, deaths, & CV events.
@DavidJoffe64 at X
https://academic.oup.com/ofid/article/doi/10.1093/ofid/ofae756/7935346
Effect of #paxlovid on adverse outcomes from #COVID19 in kidney disease. Acknowledging the limitations of a propensity-score matched study, use was associated with hospitalizations, deaths, & CV events. @DavidJoffe64 at X
https://academic.oup.com/ofid/article/doi/10.1093/ofid/ofae756/7935346
Negativ, im Rachen und in der Nase. Keine Symptome. Bin #Corona wohl noch mal entkommen. Danke Impfung & Betadine 
Meine Partnerin war dank #Paxlovid nach 3 Tagen schon negativ. Bleibt aber in Quarantäne und nimmt das Medikament für 10 Tage. Sie hatte letzten Freitag erste Symptome war also seit Donnerstag ansteckend.
“The incubation periods of COVID-19 caused by the Alpha, Beta, Delta, and Omicron variants were 5.00, 4.50, 4.41, and 3.42 days, respectively.”
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2795489
jamanetwork.comIncubation Period of COVID-19 Caused by Unique SARS-CoV-2 StrainsThis systematic review and meta-analysis estimates the incubation periods of COVID-19 caused by various strains of SARS-CoV-2.
#Paxlovid ist super. Meine Partnerin hat immer noch kein Fieber. Sie hat etwas Kopfweh und ihre Nase läuft. Der letzte Booster war im Juli.
Ich bin weiterhin negativ, hab Spass mit Betadine und grad froh das es Newgene Tests noch im fünfer Pack für unter 10 CHF gibt. 
Ich fand es süss, als Sie dachte: Ein teures Medikament kostet 100 Franken. 
Paxlovid ist 1000 bis 1500 CHF wenn die Kasse es nicht trägt. In der CH gilt, Gesundheit kostet.
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Dr. Griffin mentions that there have now been over 700 papers discussing the benefit of Paxlovid in COVID but many doctors out there somehow decided early on that Paxlovid was of no particular value or would cause a "rebound" (this is not due to Paxlovid), and these docs paradoxically refuse to allow the new information into their minds. If your doc is anti-Paxlovid, consider a new doc before you get sick. #Paxlovid **drastically** lessens the severity and mortality of #COVID.
Two studies provide more evidence of the benefit of #Paxlovid to minimize hospitalization and death in #COVID cases, particularly for older adults. https://www.cidrap.umn.edu/covid-19/paxlovid-cuts-covid-hospitalization-death-risk-and-speeds-symptom-relief-studies-find
CIDRAPPaxlovid cuts COVID hospitalization, death risk and speeds symptom relief, studies find
I keep hearing that many docs are not prescribing #Paxlovid. Why are they not better informed? It would be nice if more of them listened to Dr. Daniel Griffin's weekly updates on #TWiV
"A new retrospective cohort study conducted in Dubai shows that the antiviral nirmatrelvir plus ritonavir, sold as Paxlovid, is tied to a 61% reduction in COVID-19 hospitalization and a 58% lower rate of long COVID."
#medicine #COVID
https://www.cidrap.umn.edu/covid-19/paxlovid-tied-fewer-covid-19-hospitalizations-reduced-risk-long-covid
www.cidrap.umn.eduPaxlovid tied to fewer COVID-19 hospitalizations, reduced risk of long COVIDPaxlovid was associated with a 61% lower risk of hospitalization.
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