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#liver

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Richard Rathe

@mycotropic

Pro Tip: You don't want to megadose fat-soluble #vitamins (A, D, E & K). Bad things will happen. This is well known, well documented FACT.

Fun Fact: Early European polar explorers died of #VitaminA overdoses after eating #polarbear #liver.

"Studies indicate vitamin A levels in polar bear liver can reach 15,000 to 30,000 IU per gram, compared to the recommended daily intake of 3,000 IU for men and 2,333 IU for women, according to the National Institutes of Health (NIH). Even a small portion can cause acute toxicity."

biologyinsights.com/polar-bear

BiologyInsights · Polar Bear Liver: The Hidden Toxic DangerDiscover why consuming polar bear liver is hazardous due to its extreme vitamin A content and how it affects the human body at a biochemical level.
#Measles#StopRFK#MMR
Public
AlsoPaisleyCat

‘The Gosling Effect’ isn’t about Ryan, the Canadian actor.

It’s about the power of altruism, and the impact of Kevin Gosling, an ordinary Canadian who made a decision to make an anonymous donation of a part of his liver. His persistence changed the health care system and the way unrelated organ donors are viewed.

He is however an uncle to Ryan, in the very large Gosling extended family.

A comprehensive feature from The Ottawa Citizen reports on the transformative impact of Kevin Gosling and the others donors for whom he cleared the path.

‘A total of 2,936 organ transplants were performed in Canada in 2022. Eighty per cent of those transplants used deceased donor organs and 20 per cent used living donor organs. Fifty-two per cent of those living donors were related to the recipient. Forty-eight per cent were unrelated. . .

. . . And yet, outside of Canada, there is still a lack of understanding of how someone can be willing to give part of their organ to a complete stranger.

Dr. Nazia Selzner, who is the medical director of the live donor liver transplantation program at UHN, said she is frequently asked when he travels the world: “What is wrong with these people that they want to help someone else and go through a major surgery?”’

ottawacitizen.com/feature/the-

Ottawa Citizen · The Gosling Effect: How one man (and his liver) forever changed Canadian health careBy Elizabeth Payne
#Altruism#Good#GoodDeeds
Public
RDN

A small study found that eating an orange every day led to an improvement in fatty liver disease in 30% of the participants.

mdpi.com/2072-6643/16/18/3191

MDPIDaily Orange Consumption Reduces Hepatic Steatosis Prevalence in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease: Exploratory Outcomes of a Randomized Clinical TrialBackground: Consumption of flavonoid-rich orange juice has been shown to reduce adiposity and liver steatosis in murine models of diet-induced obesity. However, little is known about the effects of whole orange intake, independent of body weight changes, on liver function and steatosis in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD). The goal is to understand the direct impact of orange consumption on metabolic health. Methods: Sixty-two men and women aged 30–65 with MASLD (Controlled Attenuation Parameter, (CAP) > 275 dB/m) were randomly assigned to consume either 400 g of whole oranges or non-citrus fruits daily for 4 weeks. Baseline evaluations included medical assessments, blood tests, and body composition. Liver health was assessed using transient elastography (FibroScan®) for steatosis and fibrosis, conducted by blinded personnel. This clinical trial was registered at ClinicalTrials.gov (NCT05558592). Results: After 4 weeks of orange supplementation, liver steatosis decreased in the treatment group, with 70.9% showing steatosis compared to 100% in controls (p < 0.004), indicating a 30% reduction in liver disease prevalence. There were no significant changes in fibrosis or plasma liver enzymes, though plasma gamma glutaril transferase (GGT) levels decreased significantly. Body weight, waist circumference, body composition, lipid profile, fasting glucose, insulin, and C-reactive protein levels remained unchanged. Dietary analysis revealed no change in caloric intake, but vitamins C, A, thiamine, and riboflavin increased in the orange group. Conclusions: Our findings suggest that phytochemical-rich foods, especially whole fruits like oranges, may enhance liver function as an adjunct treatment for MASLD. The notable reduction in liver steatosis prevalence occurred independently of body weight changes. Further studies are needed to investigate the long-term effects of orange supplementation on steatosis and fibrosis progression and to identify the specific bioactive compounds and mechanisms involved.
#Science#Diet#Liver
Public
guyinahat

Holy #fuckabongbom! I think I have #celiacdisease.

my.clevelandclinic.org/health/

Sometime ago I stopped eating meat. I used to get also bloody stools very regularly. The doc found some elevated levels of stuff in my #liver. Then I changed my diet and stopped the meat, no onions, reduced tomatoes and other things. My liver then showed no issues. But recently I had itchy bumps in my elbow pit and neck. Also a rheumatoid arthritis - like pain on my elbow that doesn't go away. Any recommendations?

Cleveland ClinicCeliac Disease: Symptoms & How It's TreatedCeliac disease (celiac sprue, gluten-sensitive enteropathy) affects the lining of your small intestine. When your immune system attacks gluten in your intestine, it can damage it.
Public
PhoenixSerenity

#ChineseScientists successfully #transplanted the liver of #GeneEdited #pig into a 71 yr old male patient with giant right lobe #LiverCancer. The patient is moving freely without acute or hyperacute rejection reactions 7 days post surgery.

#WorldsFirst #liver #xenotransplantation #surgery of a living human. China's xenotransplantation #technology has reached a significant #breakthrough in the #medical field - #FirstAffiliatedHospital of #AnhuiMedicalUniversity.

globaltimes.cn/page/202405/131

www.globaltimes.cnChinese scientists conduct world's first liver xenotransplantation surgery for human successfully - Global Times
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DoomsdaysCW

"In 1979, an internal company report deemed #PFOS 'certainly more #toxic than anticipated' and recommended longer-term studies. That year, #3M executives flew to San Francisco to consult Harold Hodge, a respected toxicologist. They told Hodge only part of what they knew: that PFOS had sickened and even killed laboratory animals and had caused #liver abnormalities in factory workers. According to a 3M document that was marked 'CONFIDENTIAL,' Hodge urged the executives to study whether the company’s fluorochemicals caused reproductive issues or cancer. After reviewing more data, he told one of them to find out whether the chemicals were present 'in man,' and he added, 'If the levels are high and widespread and the half-life is long, we could have a serious problem.' Yet Hodge’s warning was omitted from official meeting notes, and the company’s fluorochemical production increased over time."

propublica.org/article/3m-fore

ProPublicaToxic Gaslighting: How 3M Executives Convinced a Scientist the Forever Chemicals She Found in Human Blood Were Safe
More from ProPublica
#3MLied#ForeverChemicals#PFAS
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