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#testosterone

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Any #science #endocrinology #doctor types or knowledgeable patients out there?

Have some questions before I spend money I don’t have re #DHEA & #pregnenolone.:

I’m trying to find a good compounding chemist in #Melbourne #Ausralia to compound DHEA (it’s illegal in Aus to buy off the shelf, need compounding prescription & permit- got both).

BUT! I’m getting confused by the chemists. Some say I must get a DHEA troche or a capsule will convert straight to #estrogen or #testosterone, no chance to tap DHEA receptors (unsure if they exist). I’ve also read it modulated other receptors before being metabolised.Wouldn’t I be better off w a cream in that case? Other compounders say there’s no difference. BS?

I thought #pregnenolone
might help more. It’s the ‘mother hormone’, right?
Since I caught #COVID19 I’m mostly producing low hormones but it varies. Cortisol normalised, still on thyroid meds, oestrogen shot up, no DHEA or testosterone…plus much more going on.

#MedMastodon
@medmastodon

Any #science #endocrinology #doctor types out there?

Have some questions before I spent money I don’t have:

#DHEA: Can anyone w science background/knowledgeable patient help with this?
I’m trying to find a good compounding chemist (DHEA illegal in Aus without compounding prescription & permit- got both)

BUT! I’m getting confused by the chemists. Some say I must get a DHEA troche or will convert straight to #estrogen or #testosterone as capsule, no chance to tap DHEA receptors. Ive also read it taps & modulates other receptors beforehand. Wouldn’t I be better off w a cream in that case? Other compounders say there’s no difference. BS? Halp.

I thought #pregnenolone might help more. It’s the ‘mother hormone’, right?
Since I caught #COVID19 I’m mostly producing low #hormones but it can varies (some up, others down, some normalise after a time. Cortisol normalised, still on thyroid meds, oestrogen shot up, no DHEA or testosterone… much more.

Can anyone help? I’ve been through multiple doctors, asked pharmacist and they all contradict themselves and each other or don’t know what either home does.

Don’t ever get #ChronicIllness

You’ll up relying on people who don’t know how medicine works. Very few knowledgeable people.

#MedMastodon
@medmastodon

Replied in thread

@thejessiekirk It's not always the case with injections: just the ones that trans masc folk in the UK tend to be given.

The 2 most-commonly-prescribed injections are:

Both are compounded at 250 mg/mL, but they're quite different otherwise in terms of chemical make-up, viscosity, and volume.

Sustanon is a 1 mL injection mix of refined arachis oil (peanut oil) and benzyl alcohol, containing:

  • 30 mg testosterone propionate
  • 60 mg testosterone phenylpropionate
  • 60 mg testosterone isocaproate
  • 100 mg Testosterone decanoate

It is typically administered every 2-4 weeks.

Nebido, conversely, is a 4 mL injection containing 1000 mg testosterone undecanoate, suspended in a mixture of refined castor oil and benzyl benzoate. It's typically administered every 10-12 weeks.

The main difference between these, other than the different esters of testosterone, is the viscosity of the carrier oil used.

Figures vary and there's no universal unit used for viscosity, but in all of these, castor oil is significantly more viscous than peanut oil, or MCT oil (which is commonly used in the DIY / homebrew community).

Don't know if this'll help or not, but we thought you might find it interesting :TransHeart:

www.medicines.org.ukSustanon 250, 250mg/ml solution for injection - Summary of Product Characteristics (SmPC) - (emc)Sustanon 250, 250mg/ml solution for injection - Summary of Product Characteristics (SmPC) by Aspen

Long story short there's a possibility that I end up in #Malaysia in a couple of years.

My problem:
Can I get testosterone and even maybe #trans care at a private clinic?
I know public hospitals are out of the question.

Also I haven't legally changed my gender so I don't know if "as a woman" I can get #testosterone for "menopause issues"?

Boost won't change your life but it will help mine and in a world full of transphobes it does make a difference.🙏

The Bird With Three Male Types: Scientists Discover Super Enzyme That Breaks Down Testosterone scitechdaily.com/the-crazy-bir

A single gene orchestrates #androgen variation underlying male mating morphs in ruffs science.org/doi/10.1126/scienc

"There are three types of males that differ from one another in appearance and behavior... For the 'Satellites' and 'Faeders', whose strategies aren’t based on aggressive behavior, too much #testosterone is counterproductive."