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#physiology

2 posts2 participants0 posts today
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Dave Muth

Different animal brains develop in different ways from different cells. We are surrounded by ALIEN intelligences.

Here's another brain research link, to Dr. Maria Antonietta Tosches work on brain development:
tosches-lab.com/research

The text on the page goes into digestible details. But the talk video she gives there is an hour long deep dive.

It's all cool stuff.
#Brain #Science #Neuroscience #Physiology bne.social/@phocks/11430820558

Tosches LabResearch | Tosches Lab
Public
Mark Wyner Won’t Comply :vm:

Our hearts may have brains:

“Scientists from the Karolinska Institutet in Sweden and Columbia University in the US have now uncovered a startling level of complexity among the neurons encasing the zebrafish’s heart, challenging existing theories on how the organ’s pulse is maintained in animals like ourselves…humans and zebrafish have surprisingly similar cardiovascular physiology.”

sciencealert.com/your-heart-ha

ScienceAlert · Your Heart Has Its Very Own Brain – And It's Surprisingly ComplicatedLong before we're born, our heart's tissues twitch and convulse in a rhythm that only ceases in our final hour.
#Science#Biology#Physiology
Public
SPQR

We conclude that healthy older adults show evidence of mitochondrial impairment and muscle weakness, but that this can be partially reversed at the phenotypic level, and substantially reversed at the transcriptome level, following six months of resistance exercise training.
#science #aging #exercise #physiology #biology #pathology #muscles #training #health
journals.plos.org/plosone/arti

journals.plos.orgResistance Exercise Reverses Aging in Human Skeletal MuscleHuman aging is associated with skeletal muscle atrophy and functional impairment (sarcopenia). Multiple lines of evidence suggest that mitochondrial dysfunction is a major contributor to sarcopenia. We evaluated whether healthy aging was associated with a transcriptional profile reflecting mitochondrial impairment and whether resistance exercise could reverse this signature to that approximating a younger physiological age. Skeletal muscle biopsies from healthy older (N = 25) and younger (N = 26) adult men and women were compared using gene expression profiling, and a subset of these were related to measurements of muscle strength. 14 of the older adults had muscle samples taken before and after a six-month resistance exercise-training program. Before exercise training, older adults were 59% weaker than younger, but after six months of training in older adults, strength improved significantly (P<0.001) such that they were only 38% lower than young adults. As a consequence of age, we found 596 genes differentially expressed using a false discovery rate cut-off of 5%. Prior to the exercise training, the transcriptome profile showed a dramatic enrichment of genes associated with mitochondrial function with age. However, following exercise training the transcriptional signature of aging was markedly reversed back to that of younger levels for most genes that were affected by both age and exercise. We conclude that healthy older adults show evidence of mitochondrial impairment and muscle weakness, but that this can be partially reversed at the phenotypic level, and substantially reversed at the transcriptome level, following six months of resistance exercise training.
Public
Rhyothemis

I've been thinking a lot about finding that human body temperature has been decreasing since the Industrial Revolution for a while now.
elifesciences.org/articles/495

Today I say a post about rising CO2 and wondered what effect ambient CO2 might have on Na/K ATPase. While we are taught that heat is generated in the mitochondrion via futile cycling of protons across the mt. membrane, Na/K ATPase activity also contributes. Ectotherms have lower Na/K ATPase activity than endotherms.

So I wondered if CO2 levels affect Na/K ATPase activity, and I found this -
pmc.ncbi.nlm.nih.gov/articles/

Unfortunately I don't have time to read the article and it may be weeks before I can read it.

CO2 levels have been increasing since the Industrial Revolution, Na/K ATPase activity is reduced by CO2 ( in lung epithelium) - could rising CO2 levels be causing the decrease in body temperature?
It's an interesting idea, but I would have to study a lot more to be able to gauge its plausibility.

If there is something to it - it seems like it would be a big deal, just like the decrease in body temperature is, IMO, a big deal.

eLifeDecreasing human body temperature in the United States since the Industrial RevolutionSince the Industrial Revolution, normal body temperature in both men and women has decreased monotonically by 0.03°C per birth decade.
#thermoregulation#physiology#CO2
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Dave Muth

What's does it feel like to be a robot bat?

Sweet! I wonder how life-miming this IS. What shape bat parts play the part of the triangular track in the robot? I'll put on my web-spelunking boots and climb down this rabbit hole... mastodon.social/@thebatbotlab/

(Whew! I haven't found any sci-papers comparing bat physiology and bat-robot "physiology". There are TONS of hits on a search for "adam carmody"--on Threads, Instagram, etc.)

I'm gonna need some bigger boots!
#Physiology #Bats #Maths #Flight

MastodonThe Bat Bot Lab (@thebatbotlab@mastodon.social)Attached: 1 image Design of a coupled flapping & folding mechanism for a biomimetic flapping-flight bat robot. Video: Adam Carmody.
Replied in thread
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Preston MacDougall

@ChemistryViews The genesis of #AI was the PhD advisor of #GeoffreyHinton , Christopher Longuet-Higgins who relocated to #Edinburgh from the #Chemistry Department at Cambridge to focus his research on modelling how the brain 🧠 processed information using what was then known about the #chemistry and #physiology of neurons. 👉 inf.ed.ac.uk/events/christophe

www.inf.ed.ac.ukSchool of Informatics: in memoriam Hugh Christopher Longuet-Higgins
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Public
Preston MacDougall

@Mopsi The genesis of Longuet-Higgins research was to model the way the brain 🧠 processed information using what was known about the #chemistry and #physiology of neurons. 👉 inf.ed.ac.uk/events/christophe

But you’re right, #physics is a stretch for Hinton. Hopfield is well-known in Theoretical Physics (electron transport), so that may be why the Physics Committee claimed #AI with this #NobelPrize. 🤔

www.inf.ed.ac.ukSchool of Informatics: in memoriam Hugh Christopher Longuet-Higgins
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